Links To And Excerpts From The 2018 ISDA Influenza Guidelines

Please see my other posts on Influenza:

This post contains links to and over view excerpts from Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza* [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Clin Infect Dis. 2019 Mar 5;68(6):e1-e47. doi: 10.1093/cid/ciy866.*

*The above article has been cited by 4 PubMed Central articles.

What follows are excerpts from the Guidelines.


Seasonal influenza A and B virus epidemics are associated with
significant morbidity and mortality each year in the United States and worldwide. . . . During 2010–2018, seasonal influenza epidemics were associated with an estimated 4.3–23 million medical visits, 140 000–960 000 hospitalizations, and 12000–79 000 respiratory and circulatory deaths each year in the United States [9].

Use of available diagnostic modalities and proper interpretation of results can accurately identify patients presenting with
influenza. . . . . Early treatment with antivirals reduces the duration of symptoms and risk of some complications (bronchitis, otitis media, and pneumonia) and hospitalization, and may decrease mortality among high-risk populations [13–16].

Annual vaccination is the best method for preventing or mitigating the impact of influenza, but in certain situations, chemoprophylaxis with antiviral medications can be used for preexposure or postexposure prevention and can help control outbreaks in certain populations.

The target audience includes primary care clinicians, obstetricians, emergency medicine providers, hospitalists, and
infectious disease specialists. . . . It adds new information on diagnostic testing, use of antivirals, and considerations of when to use antibiotics and when to test for antiviral resistance, and presents evidence on harm associated with routine use of corticosteroids.

Because prevention and control of influenza is a dynamic
field, clinicians should consult the website of the Centers for
Disease Control and Prevention (CDC) for the latest information about influenza vaccines, influenza tests, and approved
antiviral medications.










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