Are statins quietly lowering your GLP-1 levels? Statins are some of the most widely prescribed drugs in the world, with roughly 70 million Americans currently prescribed. While we’ve long known that these drugs can increase the risk of insulin resistance and type 2 diabetes, a 2024 study uncovered a surprising mechanism: statins appear to lower GLP-1, the same hormone targeted by drugs like Wegovy, Ozempic, and Mounjaro. In this video, Dr. Bret Scher reviews this under-discussed research and explores what it means for patients:
- Why statins may increase the risk of insulin resistance
- The role of the gut microbiome and bile acids (UDCA)
- Whether lifestyle factors like diet, sleep, and exercise can offset the risk
- Practical markers you and your doctor can monitor
It’s unfortunate that this important information hasn’t reached much of the medical community. We’re grateful to Dr. Nick Norwitz for bringing this study to light, helping ensure clinicians and researchers have the opportunity to evaluate how these findings might inform clinical practice. Expert Featured: Dr. Bret Scher
Resources Mentioned: Statins Slash GLP-1 Levels: Human Controlled Trial
