Symptoms/Manifestations	Tools or Questionnaires	Access Link
Fatigue	The Chalder Fatigue Scale^a	http://www.goodmedicine.org.uk/files/assessment,%20chalder%20fatigue%20scale.pdf
	Multidimensional Fatigue Inventory^a	http://www.cdc.gov/cfs/pdf/wichita-data-access/mfi-doc.pdf
	Fisk Fatigue Impact Scale^a	http://www.actaneurologica.be/acta/download/2003-4/01Kos%20et%20al.pdf
	The Krupp Fatigue Severity Scale^a	http://www.abiebr.com/set/17-assessment-outcomes-followingacquiredtraumatic-brain-injury/177-fatigue-severity-scale-fss
	Checklist of Individual Strength^b	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1739950/pdf/v057p00353.pdf
	DePaul Symptom Questionnaire^b,c	http://condor.depaul.edu/ljason/cfs
	CDC Symptom Inventory for CFS^b,c	http://www.institutferran.org/documentos/cdc_full_symptom_inventory.pdf
	NOVA form^d	http://www.nova.edu/nim/patients/forms/fatigue-scale.pdf
Substantial decrease or impairment in function: adults	Work and Social Adjustment Scale (WSAS)^a	serene.me.uk/tests/wsas.pdf
	Energy Index Point Score^a	http://www.treatmentcenterforcfs.com/energy_index_score
	SF-36^b (RAND-36 is available as a free version of SF-36)	http://www.sf-36.org/tools/pdf/SF-6v1_Standard_Sample.pdf
	The Lawton Instrumental Activities of Daily Living (IADL) Scale^d	http://consultgerirn.org/uploads/File/trythis/try_this_23.pdf
	Katz Index of Independence in Activities of Daily Living^d	http://clas.uiowa.edu/socialwork/files/socialwork/NursingHomeResource/documents/Katz%20ADL_LawtonIADL.pdf
	FIQR (Fibromyalgia Impact Questionnaire Revised)^d	http://fiqrinfo.ipage.com/FIQR%20FORM.pdf
Substantial decrease or impairment in function: children	Short form of the Child Health Questionnaire^b	http://jech.bmj.com/content/59/1/75.full.pdf+html
	Pediatrics Quality of Life Inventory (PedsQL)^d	http://www.pedsql.org
	Functional Disability Inventory (FDI)^d	http://www.commondataelements.ninds.nih.gov/Doc/NOC/Functional_Disability_Inventory_Parent_Form_NOC_Request.pdf
Post-exertional malaise	>CDC Symptom Inventory for CFS^b,c	http://www.institutferran.org/documentos/cdc_full_symptom_inventory.pdf
	DePaul symptom questionnaire^b,c	http://condor.depaul.edu/jason/cfs
Sleep problems	Sleep Assessment Questionnaire^d	http://www.completehealthsleep.com/DesktopModules/DocumentViewer/Documents%5CDocumentId5_%5CSleep%20Assessment%20Questionnaire.pdf
	Pittsburgh Sleep Quality Index (PSQI)^d	http://consultgerirn.org/uploads/File/trythis/try_this_6_1.pdf
	PROMIS Sleep questionnaire^d	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261577/pdf/nihms335121.pdf
Cognitive symptoms	Wood Mental Fatigue Inventory^a	http://www.pubfacts.com/detail/7902751/A-brief-mental-fatigue-questionnaire
	Checklist Individual Strength Questionnaire^b	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1739950/pdf/v057p00353.pdf
	The Cognitive Failures Questionnaire^b	http://www.yorku.ca/rokada/psyctest/cogfail.pdf
Orthostatic intolerance	Orthostatic Grading Scale^d	http://www.thestudentroom.co.uk/attachment.php?attachmentid=139109&d=1333233284
	COMPASS 31^d	http://www.nymc.edu/fhp/centers/syncope/COMPASS%2031.pdf
Pain	PROMIS^b	http://www.assessmentcenter.net
	SF-36^b	http://www.sf-36.org/tools/pdf/SF-6v1_Standard_Sample.pdf
	McGill Pain Questionnaire^d	http://www.ama-cmeonline.com/pain_mgmt/pdf/mcgill.pdf
	Brief Pain Inventory^d	http://www.npcrc.org/files/news/briefpain_short.pdf
	Pain diagram^d	http://alaska.providence.org/locations/pvmc/Documents/Pain%20Diagram.pdf

a: Questionnaires used or tested in ME/CFS patients that may be useful tools in a clinical setting.

b: Questionnaires used or tested in ME/CFS patients that may be difficult to apply in a clinical setting.

c: Questionnaires that evaluate the full range of ME/CFS symptomatology (fatigue, decrease in function, post-exertional malaise [PEM], sleep problems, cognitive symptoms, pain).

d: Questionnaires not formally tested in ME/CFS patients that may be useful tools in a clinical setting.

DQuestionnaires and Tools That May Be Useful for Assessing ME/CFS Symptoms¹

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1: Further evidence of utility is needed.

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National Academies Press (US), Washington (DC)

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Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; Board on the Health of Select Populations; Institute of Medicine. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness. Washington (DC): National Academies Press (US); 2015 Feb 10. D, Questionnaires and Tools That May Be Useful for Assessing ME/CFS Symptoms.

Tom Wade MD

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