“A Neo explains: when to use Nitric Oxide in Pulmonary Hypertension”

Today, I review. link to, and embed Tala Talks NICU‘s A Neo explains: when to use Nitric Oxide in Pulmonary Hypertension.

All that follows is from the above resource.

Feb 13, 2023

We’ve all seen the MAGIC of Inhaled Nitric Oxide at bedside, but how does it work? And how did anyone figure it out? We go over its mechanism of action (and how does viagra/ sildenafil work differently), its side effects, what dosage we use and plenty of other clinically relevant aspects of the gas.


Please be sure to give us a like, comment about future topics, and subscribe to this channel to stay up to date on all things NICU! Also, click the notification bell after you subscribe to gain your weekly NICU knowledge as soon as it’s loaded! ——————————————————————— Dr. Tala is a board-certified neonatologist and has worked in busy level III and IV units for the past 15 years. She has won multiple teaching awards throughout her time as a neonatologist.


References: Warren M. Zapol; Nitric Oxide Story. Anesthesiology 2019; 130:435–440 doi: https://doi.org/10.1097/ALN.000000000…

Sherlock LG, Wright CJ, Kinsella JP, Delaney C. Inhaled nitric oxide use in neonates: Balancing what is evidence-based and what is physiologically sound. Nitric Oxide. 2020 Feb 1;95:12-16. doi: 10.1016/j.niox.2019.12.001. Epub 2019 Dec 19. PMID: 31866361; PMCID: PMC7594166.

Barrington KJ, Finer N, Pennaforte T. Inhaled nitric oxide for respiratory failure in preterm infants. Cochrane Database Syst Rev. 2017 Jan 3;1(1):CD000509. doi: 10.1002/14651858.CD000509.pub5. PMID: 28045472; PMCID: PMC6464861.

Peliowski A; Canadian Paediatric Society, Fetus and Newborn Committee. Inhaled nitric oxide use in newborns. Paediatr Child Health. 2012 Feb;17(2):95-100. doi: 10.1093/pch/17.2.95. PMID: 23372402; PMCID: PMC3299357.

—————————————————————————- **TIMESTAMPS**

00:30  History of iNO

09:11  How does iNO work?

11:26  Side effects of iNO

14:31  How is iNO given?

16:21  When do you start iNO?

19:34  What dose of iNO do we give?

21:31 When else do we give iNO?

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