Linking To And Excerpting From Dr. Norwitz’ “Why I’m Not Afraid of Alzheimer’s Anymore”

Posted on December 5, 2025 by Tom Wade MD

Today, I review, link to, and embed Dr. Norwitz‘ Why I’m Not Afraid of Alzheimer’s Anymore.

All that follows is from the above resource.

Why I’m Not Afraid of Alzheimer’s Anymore 

Dec 5, 2025 #alzheimersdisease #apoe4 #brainhealth

For references and a written breakdown, see the associated Stay Curious Metabolism Newsletter: https://staycuriousmetabolism.substac… Lithium for Brain Health: https://staycuriousmetabolism.substac… Ketone Cleans the Brain, Video:    • How Ketones Take out the Trash: New Resear…  
I carry two copies of APOE4 — the gene variant that increases Alzheimer’s risk 10–15-fold. For years, that terrified me. But emerging research provides hope. The study we will review suggests that adding APOE2 might quiet brain inflammation, reduce plaques, and help save neurons. In today’s video, I break down the research in simple terms and what this could mean for the future of Alzheimer’s therapy. Then I’ll share the evidence-based strategies that I personally use to protect my brain while we wait for next-generation gene therapies: lithium orotate, ketosis, omega-3s, and more.
Chapters 0:00 – Why I’m Determined to Prevent Alzheimer’s 1:28 – An Incredible Picture of Neuroinflammation 2:06 – APOE2, APOE3, APOE4: What These Genes Really Mean 3:54 – The Big Question: Is There an Antidote to APOE4? 5:36 – APOE2 Therapy: Reduced Plaques & Silenced Neuroinflammation 7:19 – Chapter: The Right Insurance Saves Money and Life-Years 8:33 – My 3 Neuroprotection Essentials: Lithium, Ketosis & Omega-3s
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