“Dementia – Role of MRI” From Radiology Assistant

Posted on November 18, 2024 by Tom Wade MD

Today, I reviewed and linked to Dementia – Role of MRI from Radiology Assistant.

All that follows is from the above outstanding resource.

Dementia – Role of MRI

Frederik Barkhof, Marieke Hazewinkel, Maja Binnewijzend and Robin Smithuis

Alzheimer Centre and Image Analysis Centre, Vrije Universiteit Medical Center, Amsterdam and the Alrijne Hospital, Leiderdorp, The Netherlands

Publication date

This presentation will focus on the role of MRI in the diagnosis of dementia and related diseases.

We will discuss the following subjects:

  • Systematic assessment of MR in dementia
  • MR protocol for dementia
  • Typical findings in the most common dementia syndromes
    • Alzheimer’s disease (AD)
    • Vascular Dementia (VaD)
    • Frontotemporal lobe dementia (FTLD)
  • Short overview of neurodegenerative disorders which may be associated with dementia

All that follows is from the above resource.

Introduction

Assessment of MRI In Dementia

MRI Assessmebt in Dementia

GCA-scale for Global Cortical Atrophy

Cortical atrophy is best scored on FLAIR images.

MTA-scale for Medial Temporal lobe Atrophy

Here you can scroll through the images for examples of MTA score 0-4. This below is the eighth image in the article. Go there and scroll-it is definitely worth it.

High MTA: Alzheimer’s vs. Other Dementias

Fazekas Scale For White Matter Lesions

Normal Ageing

Strategic Infarctions

Koedam Score for Parietal Atrophy

Koedam Scale Grade 0-1

Koedam Scale Grade 2-3

FDG-PET

Specific Diseases

Alzheimers Disease

23

Presenile Dementia

Mild Cognitive Impairment

Vascular Dementia (VaD)

27

28-Strategic Infarcts

29

30

31

32 Cerebral Amyloid Angiopathy (CAA)

33

34

35 Frontotemporal Lobar Degeneration (FTLD)

36 Dementia with Lewy bodies

37 Multi System Atrophy (MSA)

38 Creutzfeldt-jakob disease (CJD)

39 New variant CJD

40 Corticobasal Degeneration (CBD)

41 Huntington Disease

42 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukencephalopathy (CADASIL)

43 Traumatic Brain Injury

44 Neuroimaging In Dementia

45 MR Protocol

46 CT Protocol

48

  1. MRI in the Practical Evaluation of Dementia: ‘Beyond Exclusion’ by Philip ScheltensView Philip Scheltens’ presentation at the 8th International Conference on Alzheimer’s Disease and Related Disorders
  2. Operational definitions for the NINDS-AIREN criteria for vascular dementia: an interobserver study.van Straaten EC, Scheltens P, Knol DL et al. Stroke 2003; 34: 1907-1912.
  3. A New Rating Scale for Age-Related White Matter Changes Applicable to MRI and CTL. O. Wahlund, MD, PhD; F. Barkhof, MD, PhD; F. Fazekas, MD et al
    on behalf of the European Task Force on Age-Related White Matter Changes.
    Stroke. 2001;32:1318
  4. Small Vessel Disease and General Cognitive Function in Nondisabled ElderlyWiesje M. van der Flier, PhD et al
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    State of the Art article in Radiology 2003;226:315-336.
  6. Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADCG B Frisoni, P h Scheltens, S Galluzzi, F M Nobili et al.
    Journal of Neurology Neurosurgery and Psychiatry 2003;74:1371-1381
  7. Medial temporal lobe atrophy on MRI in dementia with Lewy bodiesBarber R et al. Neurology 1999;52:1153
  8. Thalamic Lesions in Vascular Dementia. Low Sensitivity of Fluid-Attenuated Inversion Recovery (FLAIR) ImagingAnt?nio J. Bastos Leite, MD et al.
    Stroke. 2004;35:415
  9. Order Magnetic Resonance in Dementia at Amazon.comby Jaap Valk, Frederik Barkhof, Philip Scheltens.
  10. Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study.Inzitari D, Simoni M, Pracucci G, Poggesi A, Basile AM, Chabriat H, Erkinjuntti T, Fazekas F, Ferro JM, Hennerici M, Langhorne P, O’Brien J, Barkhof F, Visser MC, Wahlund LO, Waldemar G, Wallin A, Pantoni L; LADIS Study Group.
    Arch Intern Med. 2007 Jan 8;167(1):81-8
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    for Medical Education of the Florida State University College of Medicine
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    Clin Radiol. 2001 Sep;56(9):726-39.
  13. Clinical Neuroradiology, Gasser M. Hathout, 2009 Pp103-114
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  15. Posterior cerebral atrophy in the absence of medial temporal lobe atrophy in pathologically-confirmed Alzheimer’s diseaseby Lehmann M, Koedam EL, Barnes J, Bartlett JW, Ryan NS, Pijnenburg YA, Barkhof F, Wattjes MP, Scheltens P, Fox NC.
    Source
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