“Glomerulonephritis” Lecture From The Children’s Hospital Of Philadelphia With Additional Resources

For a complete list of the outstanding pediatric FOAM courses from the Children’s Hospital of Philadelphia, please see CHOP Open-access Medical Education.

Here is a link to the Glomerulonephritis Lecture and Slides from The Children’s Hospital of Philadelphia.

It is best to watch and listen to the lecture on a screen initially for retention. There are 70 slides which you can quickly review when you want to refresh your memory.

The lecture is good but basically, all a primary care pediatrician needs to know (except when taking exams) is how to make the diagnosis and then refer to a pediatriac nephrologist.

What follows is from Pediatric Glomerulonephritis, April 19, 2018 from emedicine.medscape.com:

Practice Essentials

Nephritis is an older term used to clinically denote a child with hypertension, decreased renal function, hematuria, and edema. Technically, nephritis suggests a noninfectious inflammatory process that involves the nephron; glomerulonephritis(GN) generally is a more precise term. (See Etiology.)

Diseases that produce GN are usually classified as primary (ie, diseases in which the kidney is the primarily affected organ) or secondary (ie, systemic disorders that involve the kidneys in addition to other organs, such as systemic lupus erythematosus [SLE]). (See Differentials, Workup.)

Currently, most children with hematuria and decreased renal function who do not have a presentation consistent with postinfectious GN receive a renal biopsy, leading to a specific pathologic diagnosis. In these cases, the general terms GN and nephritis are not specific enough to be very useful for treatment or prognosis. (See Etiology, Workup.)

The term nephritis is also applied to a group of unrelated inflammatory disorders known collectively as tubulointerstitial nephritis (TIN). TIN initially affects mainly the interstitium and renal tubules.

Epidemiology

In the United States, the incidence and prevalence of glomerulonephritis (GN) in the pediatric population is unknown. Acute postinfectious (most often poststreptococcal) GN has diminished in recent years but is still the most frequent type of GN. Other conditions sometimes presenting with GN, such as Henoch-Schönlein purpura, immunoglobulin A (IgA) nephropathy, [1Alport syndrome, and SLE, as well as membranoproliferative GN and mesangial proliferative GN, occur infrequently.

So here are a few of the basic slides from the lecture:

Slide 3

Slide 4:

Slide 9:

Slide 12:

Slide 50:

I’ve made several posts on Henoch-Schonlein Purpura [Link is to the search list]. And see Henoch Schonlein Purpura – Some Pearls, Resources, And A Guideline From RCHM
Posted on June 20, 2017 by Tom Wade MD. These resources have much more detail than the present lecture.

Slide 51:

Slide 68:

Slide 69:

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