Links To The Internet Book Of Critical Care’s Chapter “Neuroleptic Malignant Syndrome (NMS)”

In this post, I review and link to Dr. Josh Farkas‘ Internet Book Of Critical Care (IBCC) chapter, Neuroleptic Malignant Syndrome (NMS), April 17, 2021.

All that follows is from the above resource.

Neuroleptic malignant syndrome is rare, but this will be encountered in the ICU.  Particularly with the rising utilization of antipsychotics for a variety of indications (e.g., emesis, agitation), we should be cognizant of this entity.  Another relevent cause of NMS is abrupt withdrawal of Parkinson’s medications (e.g., due to NPO status).

CONTENTS

• Pathophysiology
• Epidemiology
• Clinical features
• Laboratory abnormalities
• Differential diagnosis & evaluation
• Diagnostic criteria
• Management
  • Supportive care
  • Bromocriptine
  • Dantrolene
  • Electroconvulsive therapy
• Podcast
• Questions & discussion
• Pitfalls