“Post-Exertional Malaise (PEM)” By Dr. Brayden Yellman

In this post, I link to and excerpt from Dr. Brayden Yellman’s Post-Exertional Malaise (PEM), 40:24, May 17, 2022.

In this presentation, Brayden Yellman, MD, reviews:

– The definition of PEM
– PEM presentation in post-acute sequelae of COVID-19 (PASC/long COVID), ME/CFS, and related post-viral syndromes (PVS)
– Triggers and PEM onset
– The science behind PEM: VAT reductions, decreased aerobic metabolism, altered cellular metabolism, neurobiological changes, dorsal midbrain activity post-exercise
– Clinical implications of PEM
– How to clinically manage PEM

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