The two resources below discuss the presence and meaning of Anti CD320 antibodies as a cause of CNS B12 deficiency in the face of normal serum B12 levels.
Please see and review Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency [PubMed Abstract] [Full-Text HTML] [Full-Text PDF]. Sci Transl Med. 2024 Jun 26;16(753):eadl3758. doi: 10.1126/scitranslmed.adl3758. Epub 2024 Jun 26.
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Today, I review, link to, and embed Transcobalamin Receptor Antibodies in Autoimmune Vitamin B12 Central Deficiency, Jul 22, 2024 Neurology Podcast.
All that follows is from the above resource.
Jul 22, 2024 Neurology PodcastDr. Justin Abbatemarco talks with Drs. Michael R. Wilson and John Pluvinage about their discovery of anti-CD320 antibodies in patients with neurologic manifestations of B12 deficiency and discuss the potential implications for diagnosis and treatment.