Link To The Results Of A PubMed Search “low dose oral minoxidil for alopecia”

Posted on September 8, 2022 by Tom Wade MD

In this post, I link to a PubMed search I conducted today, “low dose oral minoxidil for alopecia.” There were 35 articles returned.

All that follows is from the PubMed search.

Oralminoxidil treatment for hair loss: A review of efficacy and safety.

Randolph M, Tosti A.J Am Acad Dermatol. 2021 Mar;84(3):737-746. doi: 10.1016/j.jaad.2020.06.1009. Epub 2020 Jul 2.PMID: 32622136 Review.
OBJECTIVE: In recent years, oral minoxidil at low dose has been proposed as a safe alternative. This study reviewed articles in which oral minoxidil was used to treat hair loss to determine its efficacy and safety as an alternative to top …

Low–doseoralminoxidil as treatment for non-scarring alopecia: a systematic review.

Sharma AN, Michelle L, Juhasz M, Muller Ramos P, Atanaskova Mesinkovska N.Int J Dermatol. 2020 Aug;59(8):1013-1019. doi: 10.1111/ijd.14933. Epub 2020 Jun 9.PMID: 32516434
BACKGROUND: Topical minoxidil has been used for almost 40 years to treat alopecia. There is growing evidence supporting off-label use of low–dose oral minoxidil. …Oral minoxidil dose ranged from 0.25 to 5 mg daily t …

Safety of low–doseoralminoxidil for hair loss: A multicenter study of 1404 patients.

Vañó-Galván S, Pirmez R, Hermosa-Gelbard A, Moreno-Arrones ÓM, Saceda-Corralo D, Rodrigues-Barata R, Jimenez-Cauhe J, Koh WL, Poa JE, Jerjen R, Trindade de Carvalho L, John JM, Salas-Callo CI, Vincenzi C, Yin L, Lo-Sicco K, Waskiel-Burnat A, Starace M, Zamorano JL, Jaén-Olasolo P, Piraccini BM, Rudnicka L, Shapiro J, Tosti A, Sinclair R, Bhoyrul B.J Am Acad Dermatol. 2021 Jun;84(6):1644-1651. doi: 10.1016/j.jaad.2021.02.054. Epub 2021 Feb 24.PMID: 33639244
BACKGROUND: The major concern regarding the use of low–dose oral minoxidil (LDOM) for the treatment of hair loss is the potential risk of systemic adverse effects. …The dose of LDOM was titrated in 1065 patients, allowing the analysis of 2469 …

Review of oralminoxidil as treatment of hair disorders: in search of the perfect dose.

Villani A, Fabbrocini G, Ocampo-Candiani J, Ruggiero A, Ocampo-Garza SS.J Eur Acad Dermatol Venereol. 2021 Jul;35(7):1485-1492. doi: 10.1111/jdv.17216. Epub 2021 Mar 23.PMID: 33660357 Review.
Even though it is an effective therapy, many patients show poor compliance due to the cosmesis, cost and side-effects. During the last few years, low–dose oral minoxidil has proven to be an alternative for patients with alopecia. We performed a …

Female pattern hair loss: a pilot study investigating combination therapy with low–doseoralminoxidil and spironolactone.

Sinclair RD.Int J Dermatol. 2018 Jan;57(1):104-109. doi: 10.1111/ijd.13838. Epub 2017 Dec 12.PMID: 29231239
BACKGROUND: Minoxidil and spironolactone are oral antihypertensives known to stimulate hair growth. OBJECTIVE: To report on a case series of women with pattern hair loss (PHL) treated with once daily minoxidil 0.25 mg and spironolactone 25 mg. METHODS: Women …

Minoxidil: a comprehensive review.

Gupta AK, Talukder M, Venkataraman M, Bamimore MA.J Dermatolog Treat. 2022 Jun;33(4):1896-1906. doi: 10.1080/09546634.2021.1945527. Epub 2021 Jul 20.PMID: 34159872 Review.
The 5% solution and foam were not significantly different in efficacy from the 2% solution.Oral and Sublingual minoxidil (not FDA approved; off-label): After 6 months of administration, minoxidil 5 mg/day was significantly more effective than topical 5% and 2 …

Efficacy and Safety of OralMinoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment.

Panchaprateep R, Lueangarun S.Dermatol Ther (Heidelb). 2020 Dec;10(6):1345-1357. doi: 10.1007/s13555-020-00448-x. Epub 2020 Sep 24.PMID: 32970299 Free PMC article.
INTRODUCTION: Oral minoxidil is an antihypertensive vasodilator known to stimulate hair growth. The use of low–dose oral minoxidil for the treatment of male androgenetic alopecia (AGA) is receiving increasing attention. …

Safety of low–doseoralminoxidil treatment for hair loss. A systematic review and pooled-analysis of individual patient data.

Jimenez-Cauhe J, Saceda-Corralo D, Rodrigues-Barata R, Moreno-Arrones OM, Ortega-Quijano D, Fernandez-Nieto D, Jaen-Olasolo P, Vaño-Galvan S.Dermatol Ther. 2020 Nov;33(6):e14106. doi: 10.1111/dth.14106. Epub 2020 Sep 7.PMID: 32757405
low dose oral minoxidil (OM) is an increasingly used treatment for androgenetic alopecia and other types of hair loss. to analyze available data of patients treated with OM, focusing on safety and adverse effects. a search in PubMed and EMBASE w …

Male Androgenetic Alopecia.

Cranwell W, Sinclair R.2016 Feb 29. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dhatariya K, Dungan K, Hershman JM, Hofland J, Kalra S, Kaltsas G, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, Morley JE, New M, Purnell J, Sahay R, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–.PMID: 25905192 Free Books & Documents. Review.
While many men choose not to undergo treatment, topical minoxidil and oral finasteride are approved by the Food and Drug Administration (USA) for the treatment of MAA. …DHT binding to the scalp hair follicle androgen receptors produces MAA. A daily oral fin …

Low–dose daily aspirin reduces topical minoxidil efficacy in androgenetic alopecia patients.

Goren A, Sharma A, Dhurat R, Shapiro J, Sinclair R, Situm M, Kovacevic M, Lukinovic Skudar V, Goldust M, Lotti T, McCoy J.Dermatol Ther. 2018 Nov;31(6):e12741. doi: 10.1111/dth.12741. Epub 2018 Oct 8.PMID: 30226287
Topical minoxidil is the only US FDA approved OTC drug for the treatment of androgenetic alopecia (AGA). …However, following 14 days of aspirin administration, only 27% of the subjects were predicted to respond to topical minoxidil. To the best of our knowl …
Platelet-rich plasma with lowdoseoralminoxidil (1.25mg versus 2.5mg) along with trichoscopic pre- and post-treatment evaluation.

Jha AK, Zeeshan M, Singh A, Roy PK.J Cosmet Dermatol. 2021 Oct;20(10):3220-3226. doi: 10.1111/jocd.14049. Epub 2021 Mar 18.PMID: 33682223
BACKGROUND: Low dose (<5 mg) oral minoxidil (OM) seems a promising option for male androgenetic alopecia (MAGA). AIM: To evaluate the role of oral minoxidil 1.25 mg versus oral minoxidil 2.5 mg along with platelet- …

Efficacy and safety of oralminoxidil in female androgenetic alopecia.

Vastarella M, Cantelli M, Patrì A, Annunziata MC, Nappa P, Fabbrocini G.Dermatol Ther. 2020 Nov;33(6):e14234. doi: 10.1111/dth.14234. Epub 2020 Sep 14.PMID: 32851744
Oral minoxidil (OM) has been reported to be effective for androgenetic alopecia (AGA). …Twelve women (aged 18-66 years; mean age 36.66 18.79 years) with AGA (Ludwig scale I-3-III) were recruited. The starting dose of minoxidil was 0.50 mg dail …

Topical and oralminoxidil for hair disorders in pediatric patients: What do we know so far?

Lemes LR, Melo DF, de Oliveira DS, de La-Rocque M, Zompero C, Ramos PM.Dermatol Ther. 2020 Nov;33(6):e13950. doi: 10.1111/dth.13950. Epub 2020 Jul 14.PMID: 32614119 Review.
In dermatology, topical minoxidil (TMX) has been used for many types of alopecia. TMX is not FDA-approved in patients under 18 years old and there are no guidelines for its pediatric use. Low–dose oral minoxidil (OMX) has been used off-la …

Treatment of permanent chemotherapy-induced alopecia with lowdoseoralminoxidil.

Yang X, Thai KE.Australas J Dermatol. 2016 Nov;57(4):e130-e132. doi: 10.1111/ajd.12350. Epub 2015 May 13.PMID: 25966934
Permanent chemotherapy-induced alopecia (PCIA) is the absence of or incomplete hair regrowth lasting longer than 6 months after the cessation of chemotherapy and it does not respond to standard treatments of scalp cooling or topical minoxidil. …We report a case of …

Eyebrow Regrowth in Patients with Frontal Fibrosing Alopecia Treated with Low–DoseOralMinoxidil.

Pirmez R, Spagnol Abraham L.Skin Appendage Disord. 2021 Feb;7(2):112-114. doi: 10.1159/000511744. Epub 2020 Dec 2.PMID: 33796556 Free PMC article.
Partial or complete eyebrow loss is seen in most patients with frontal fibrosing alopecia (FFA). Despite the scarring nature of FFA, eyebrow hair regrowth has been previously reported. …CASE PRESENTATION: We report eyebrow regrowth in 7 patients with FFA treated with …
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