Please also review:
- Nonarteritic Anterior Ischemic Optic Neuropathy from StatPearls. Kirandeep Kaur; Edward Margolin. Last Update: September 14, 2025.
- Glucagon-Like Peptide-1 Receptor Agonists and the Risk of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Consensus Statement by NANOS and the American Academy of Ophthalmology [PubMed Abstract] [Full-Text HTML] [Download Full-Text PDF]. Ophthalmology. 2026 Aug;133(8):1029-1035. doi: 10.1016/j.ophtha.2026.04.008. Epub 2026 May 14.
- Giant Cell Arteritis from the American Academy of Ophthalmology‘s EyeWiki. Assigned status Up to Date. By Anne Barmettler, MD on April 20, 2026.
- “Differential Diagnosis: The most common disease in the differential diagnosis of GCA with decreased vision is NAION.Important features that may help to differentiate arteritic ischemic optic neuropathy (AAION) from non-arteritic ischemic optic neuropathy (NAION).
Table 1. Important features that may help to differentiate arteritic ischemic optic neuropathy (AAION) from non-arteritic ischemic optic neuropathy (NAION).
- As shown in Table 1, NAION is associated with small-crowded optic nerves, hypertension, diabetes, and hyperlipidemia,[31] whereas AAION is not necessarily associated with the same vascular risk factors. In addition, patients with GCA are typically older than those with NAION (i.e. 8th–9th decade vs. 6th–7th decade). In NAION, patients will usually not note any associated systemic symptoms such as headache, jaw claudication, scalp tenderness, weight loss, anorexia, fever, or myalgias/arthralgias. In general, the vision loss from GCA is more severe than with NAION, with one third of patients with AAION demonstrating a visual acuity worse than 20/200; most patients with NAION retain a visual acuity near 20/80.[118] Patients with AAION may complain of preceding amaurosis fugax as well as other ocular symptoms including diplopia, fellow eye involvement, or ophthalmoplegia.The physical examination also differs between these two diseases. Whereas AAION is associated with a diffuse “chalky” white edema, eventual cupping of the disc, and possible coexistent retinal ischemia, NAION often demonstrates segmental optic nerve edema with eventual sectoral or total flattening and pallor.[36][58] In addition, laboratory evaluations such as ESR and CRP are usually normal in patients with NAION.Other systemic causes of vasculitis can present with similar systemic and possibly ophthalmic manifestations to GCA (e.g., rheumatoid arthritis, systemic lupus erythematosus, polyarteritis nodosa, polymyositis, Takayasu arteritis).[31] In addition, malignancy, systemic infections, dental disease, trigeminal neuralgia, and amyloidosis should be considered in the appropriate clinical setting.
- “Differential Diagnosis: The most common disease in the differential diagnosis of GCA with decreased vision is NAION.Important features that may help to differentiate arteritic ischemic optic neuropathy (AAION) from non-arteritic ischemic optic neuropathy (NAION).
Today, I review, link to, and embed Dr. Brad Stanfield‘s excellent YouTube lecture “David Sinclair Says Ozempic Causes Blindness”. And Dr. Stanfield emphatically states that David Sinclair is wrong. I have added some of Dr. Stanfield’s slides below. But each person needs to carefully review Dr. Stanfield’s video and make his or her own decision.
All that follows is from the above resource.
Sinclair Says Ozempic Causes Blindness
Aug 20, 2026✔️ Patreon:/ bradstanfieldmd
I strongly recommend you review Dr. Stanfield’s excellent transcript which is available when you watch his lecture on YouTube. And be sure to review the additional resource links at the beginning of this post.
