Link To And Resources From “#153 Heart Disease in Women” – A Great Ischemic Heart Disease Minicourse From The Curbsiders With Additional Resources

This post consists of a link to the outstanding lecture #153 Heart Disease in Women with Dr Bairey Merz. JUNE 3, 2019 By DR MOLLY HEUBLEIN from The Curbsiders with additional resources.

In addition, in this post, I’ve listed many of the resources cited in the course and made blog posts excerpting from those resources. The relevant links follow the resource cited below.

The minicourse on ischemic heart disease, to me consists of:

  • Listening to the podcast
  • Reviewing the show notes
  • Reading all of the articles referenced in the show notes. [I have included links to all the excellent articles referenced in the show notes.]

The figure below is from Resource (3) below, How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial. Interv Cardiol. 2019 May; 14(2): 76–82.

Resource (3) the source of the figure below is from interventional cardiologists who, not surprisingly, recommend that the diagnoses below be made with invasive catheter based measurements. I will be seeing later what the response of non-catheterizing cardiologists are. But regardless of the authors motivation, it is a great chart that well summarizes the topic.

All the references below excerpt for (2) and (3)  are from Episode #153’s outstanding show notes. To get maximum benefit from this episode, each listener should carefully read all of the articles below:

1. Myocardial Ischemia in Women – Lessons from the NHLBI WISE Study [Pubmed Abstract] [Full Text HTML] [Full Text PDF]. Clin Cardiol. 2012 Mar;35(3):141-8. doi: 10.1002/clc.21966.

The above article has been cited by 22 PubMed Central articles.

Please see my post (my study notes), for excerpts from this article, Links To And Excerpts From “Myocardial Ischemia in Women – Lessons from the NHLBI WISE Study”
Posted on June 18, 2019 by Tom Wade MD

2.  Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study [PubMed Abstract] [Full Text HTML] [Full Text PDF]. J Am Heart Assoc. 2016 Mar 15;5(3):e003064. doi: 10.1161/JAHA.115.003064.

The above article has been cited by 15 PubMed Central articles.

Please see my post (my study notes), for excerpts from this article, Links To And Excerpts From “Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study”
Posted on June 18, 2019 by Tom Wade MD

3. How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Interv Cardiol. 2019 May 21;14(2):76-82. doi: 10.15420/icr.2019.04.R1. eCollection 2019 May.

Please see my post (my study notes), for excerpts from this article, Links To And Excerpts From “How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial”
Posted on June 18, 2019 by Tom Wade MD

4. Angina with “normal” coronary arteries: a changing philosophy [PubMed Abstract] [Full Text HTML] [Full Text PDF]. JAMA. 2005 Jan 26;293(4):477-84.

The above article has been cited by 85 articles in PubMed Central

Please see my post (my study notes), for excerpts from this article, Links To And Excerpts From ‘Angina with “normal” coronary arteries: a changing philosophy’
Posted on June 18, 2019 by Tom Wade MD

5. Endogenous Sex Hormones and Incident Cardiovascular Disease in Post-Menopausal Women [PubMed Abstract] [Full Text HTML] [Full Text PDF]. J Am Coll Cardiol. 2018 Jun 5;71(22):2555-2566. doi: 10.1016/j.jacc.2018.01.083.

The above article has been cited by 8 PubMed Central Articles.

CONCLUSIONS

Among post-menopausal women, a higher testosterone/estradiol ratio was associated with an elevated risk for incident CVD, CHD, and HF events, higher levels of testosterone associated with increased CVD and CHD, whereas higher estradiol levels were associated with a lower CHD risk. Sex hormone levels after menopause are associated with women’s increased CVD risk later in life.

DISCUSSION

Although sex hormone levels may be linked to future CVD events, it is unclear what the best intervention is to modify sex hormone levels for risk reduction.

6.  Sex Differences in Hemodynamic and Microvascular Mechanisms of Myocardial Ischemia induced by Mental Stress [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Arterioscler Thromb Vasc Biol. 2018 Feb; 38(2): 473–480.

The above article has been cited by 6 PubMed Central Articles.

7. Third universal definition of myocardial infarction [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Eur Heart J. 2012 Oct;33(20):2551-67. doi: 10.1093/eurheartj/ehs184. Epub 2012 Aug 24.

Please see my post (my study notes), for excerpts from this article, “Electrocardiographic detection of myocardial infarction” From “Third universal definition of myocardial infarction”
Posted on June 23, 2019 by Tom Wade MD

8. ESC working group position paper on myocardial infarction with non-obstructive coronary arteries [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Eur Heart J. 2017 Jan 14;38(3):143-153. doi: 10.1093/eurheartj/ehw149.

The above article has been cited by 22 PubMed Central articles.

Please see my post (my study notes), for excerpts from this article, Links To And Excerpts From “ESC working group position paper on myocardial infarction with non-obstructive coronary arteries”
Posted on June 18, 2019 by Tom Wade MD

10. Alternative causes of myocardial ischemia in women: An update on spontaneous coronary artery dissection, vasospastic angina and coronary microvascular dysfunction [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Vasc Med. 2017 Apr;22(2):146-160. doi:10.1177/1358863X16686410.

11. Spontaneous coronary artery dissection: from expert consensus statements to evidence-based medicine [PubMed Abstract] [Full Text HTML] [Full Text PDF]. J Thorac Dis. 2018 Jul;10(7):4602-4608. doi: 10.21037/jtd.2018.07.10.

12. The Role of Cardiac MRI in Patients with Troponin-Positive Chest Pain and Unobstructed Coronary Arteries [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Curr Cardiovasc Imaging Rep. 2015;8(8):28.

The above article has been cited by 5 articles in PubMed Central.

13. Comparison of frequency of inducible myocardial ischemia in patients presenting to emergency department with typical versus atypical or nonanginal chest pain [PubMed Abstract]. Am J Cardiol. 2010 Jun 1;105(11):1561-4. doi: 10.1016/j.amjcard.2010.01.014. Epub 2010 Apr 10.

The above article has been cited by 3 articles in PubMed Central.

14. Development and Validation of a Short Version of the Seattle Angina Questionnaire [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Circ Cardiovasc Qual Outcomes. 2014 Sep;7(5):640-7. doi: 10.1161/CIRCOUTCOMES.114.000967. Epub 2014 Sep 2.

15. ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/ SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart disease [PubMed Abstract] [Full Text HTML] [Full Text PDF]. J Am Coll Cardiol. 2014 Feb 4;63(4):380-406. doi: 10.1016/j.jacc.2013.11.009. Epub 2013 Dec 16.

The above article has been cited by 88 PubMed Central articles.

16. The Duke Treadmill Score from MDCalc

17. Coronary CT Angiography and 5-Year Risk of Myocardial Infarction from The SCOT-HEART Investigators [PubMed Abstract] [Full Text HTML] [Full Text PDF]. N Engl J Med. 2018 Sep 6;379(10):924-933. doi: 10.1056/NEJMoa1805971. Epub 2018 Aug 25.

The above article has been cited by 7 articles in PubMed Central.

Please see my post (my study notes), for resources about this article, Links To And Abstract From The SCOT-HEART Trial With Additional Resources
Posted on July 1, 2019 by Tom Wade MD

Start here: (Nihoyannopoulos 1991Mittal 2015).

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