The Ultimate Hepatology Minicourse From The Curbsiders And Other Resources

The ultimate hepatology minicourse is from the Curbsiders and from hepatologist and master teacher Dr. Scott Matherly along with other resources I’ve reviewed for the minicourse. I’ve embedded Dr. Mattherly’s podcasts here along with links to the outstanding Curbsiders show notes.

#100: Cirrhosis: Initial Evaluation and Management [Link is to the show notes and pocast]
JUNE 18, 2018 By CYRUS ASKIN from The Curbsiders

#101: Cirrhosis: Medications, decompensation, complications
JUNE 25, 2018 By CYRUS ASKIN [Link is to the show notes and pocast]

#142 Cirrhosis TIPS for Acute Complications [Link is to the show notes and pocast]
MARCH 11, 2019 By NORA TARANTO

Some Definitions, first: (from the 2015 Baveno guidelines)

Compensated Cirrhosis:

Diagnosed with cirrhosis based on history, physical exam, and lab abnormalities but without history of ascites, encephalopathy, or variceal bleeding. Prognosis is good in the long term (survival measured in decades). Compensated cirrhosis can be broken down into those with and without varices (D’Amico et al, 2006), or with or without portal hypertension.

Decompensated Cirrhosis:

Cirrhosis with ascites, hepatic encephalopathy, or variceal bleeding. Prognosis becomes poorer once patients experience one of these, and these patients benefit from evaluation for transplant. (n.b. Patients can move fluidly between these categories. An alcoholic patient with decompensated cirrhosis who then stops drinking, or a patient with Hepatitis C who starts the anti-viral therapy, may experience dramatic improvements in a short amount of time. These patients might be considered compensated after several years.

Late Decompensated Cirrhosis:

Cirrhosis with recurrent variceal bleeds, refractory ascites, hepatorenal syndrome, recurrent hepatic encephalopathy, or continuous jaundice. Much poorer prognosis (survival measured in months or less). These patients require immediate consideration for transplant.

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Also in this post I link to some of my previous resources posted in the category Hepatology: [I use review of the resources below for my hepatology minicourse.

Early Recognition And Prompt Referral Of Acute Liver Failure – Guidelines From The AASLD
Posted on October 22, 2018 by Tom Wade MD

Hepatitis from Lab Tests Online by the American Association Of Clinical Chemistry

When And How To Test For Hepatitis B and C – Help From The CDC
Posted on January 6, 2019 by Tom Wade MD

Liver Transplant Podcast – with Dr. David Gerber and Dr. Skip Hayashi              Posted on March 23, 2019 by Tom Wade MD

MELD Score (Model For End-Stage Liver Disease) (12 and older) From MDCalc
Posted on March 24, 2019 by Tom Wade MD

“Cirrhosis and autoimmune liver disease: Current understanding” From The World Journal Of Hepatology
Posted on March 25, 2019 by Tom Wade MD

Imaging Of Liver Disease -links to  The American College Of Radiology and to the Complete List Of Diagnostic Appropriateness Criteria

Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases [PubMed Abstract] [Full Text HTML] [Full Text PDF]. Hepatology. 2018 Aug;68(2):723-750. doi: 10.1002/hep.29913.

The above article has been cited by 91 PubMed Central articles.

“Diagnosis of cirrhosis and portal hypertension: imaging, non-invasive markers of fibrosis and liver biopsy” From Gastroenterology Report
Posted on March 26, 2019 by Tom Wade MD

“Expanding consensus in portal hypertension” From The Journal Of Hepatology
Posted on March 26, 2019 by Tom Wade MD

The Causes Of Ascites – “Serum Ascites Albumin Gradient (SAAG) Interpretation” From Emedicine.Medscape.com
Posted on April 3, 2019 by Tom Wade MD

Resources For Portal Venous Exam By Ultrasound
Posted on April 23, 2019 by Tom Wade MD

Summary Statements From And Link To “The Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance From the American Association for the Study of Liver Diseases” With An Additional Resource
Posted on April 24, 2019 by Tom Wade MD

Excerpts From The 2017 Guidelines On The Evaluation Of Abnormal Liver Tests From The ACG
Posted on April 26, 2019 by Tom Wade MD

Links To Articles On Autoimmune Hepatitis
Posted on April 27, 2019 by Tom Wade MD

Links To And Excerpts From “Mildly Elevated Liver Transaminase Levels: Causes and Evaluation” From American Family Physician
Posted on August 23, 2019 by Tom Wade MD

Links To And Excerpts From the 2018 “Guidelines on the management of abnormal liver blood tests” From The British Society of Gastroenterology
Posted on August 24, 2019 by Tom Wade MD

“5 Pearls On Hepatic Encephalopathy” From CoreIM With Excerpts From The 2014 AASLD Guidelines
Posted on November 13, 2019 by Tom Wade MD

Who And How To Screen For Chronic Hepatitis B – Help From The CDC and CoreIM’s Chronic Hepatitis B, Part 1
Posted on November 13, 2019 by Tom Wade MD

5 Pearls on Chronic Hepatitis B, Part 2 Management from CoreIM, January 31, 2018. [Link is to the podcast and show notes.]

 

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